Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | MGMT | P16455 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860314 | 0.79 | POLB (0.45) | MAPTMAPK1ALDH1A1LMNACYP1A2 | |
| SCHEMBL5858886 | 0.76 | BRD4 (0.42) | GAALMNACYP3A4 | |
| SCHEMBL6753015 | 0.69 | BRD4 (0.62) | MAPTMAPK1LMNACYP1A2CYP2D6 | |
| SCHEMBL18941364 | 0.67 | POLB (0.46) | MAPTALDH1A1LMNACYP1A2CYP3A4 | |
| SCHEMBL28900810 | 0.66 | BRD4 (0.62) | MAPK1LMNACYP1A2CYP2D6TSHR | |
| SCHEMBL9435393 | 0.65 | PIN1 (0.58) | HDAC1HDAC2CDK1LMNACYP1A2 | |
| SCHEMBL8583453 | 0.65 | GDA (0.57) | — | |
| SCHEMBL5841120 | 0.65 | TP53 (0.49) | MAPTPOLB | |
| SCHEMBL18941373 | 0.63 | LMNA (0.33) | MAPTTDP1MAPK1ALDH1A1LMNA | |
| SCHEMBL8606310 | 0.62 | ADORA3 (0.44) | CDK1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3143038-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | Ugisense AG (DE) | 2017-03-22 | — | — | EP | claimed |
| WO-2015172889-A1 | PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS | UGICHEM GMBH (AT) | 2015-11-19 | — | — | WO | claimed |