Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 11/20 | 0.62 |
| ▸ | NT5C2 | P49902 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28900808 | 0.81 | BRD4 (0.39) | BRD4NT5C2LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL6753015 | 0.78 | BRD4 (0.62) | BRD4NT5C2LMNAHSD17B10NT5E | |
| SCHEMBL29514799 | 0.77 | BRD4 (1.00) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL6463477 | 0.76 | BRD4 (0.92) | BRD4NT5C2NT5ECREBBPTOP2A | |
| SCHEMBL8381776 | 0.76 | BRD4 (0.97) | BRD4NT5C2NT5ECREBBPNPC1 | |
| SCHEMBL3038563 | 0.76 | NPC1 (0.76) | BRD4NT5C2LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL22118772 | 0.75 | BRD4 (0.68) | BRD4NT5C2SMN1; SMN2HSD17B10NT5E | |
| SCHEMBL28478879 | 0.75 | GDA (0.57) | — | |
| SCHEMBL7778558 | 0.75 | SMN1; SMN2 (0.64) | BRD4NT5C2LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL7781149 | 0.74 | LMNA (0.63) | BRD4NT5C2LMNASMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074911-B | Peptide nucleic acid monomers and oligomers | 优基艾森斯股份公司 | 2020-11-03 | — | — | CN | claimed |
| CN-107074911-B | Peptide nucleic acid monomers and oligomers | 优基艾森斯股份公司 | 2020-11-03 | — | — | CN | disclosed |