SCHEMBL1726336

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9886771	0.86	VCAM1 (0.55)	VCAM1MAPTMEN1KMT2ACYP1A2
	SCHEMBL9523948	0.83	EPAS1 (0.53)	VCAM1GRM8GRM6GRM4MAPT
	SCHEMBL16950945	0.83	VCAM1 (0.53)	VCAM1GRM8GRM6GRM4MAPT
	SCHEMBL20856478	0.82	VCAM1 (0.51)	VCAM1GRM8GRM6GRM4MAPT
	SCHEMBL11460934	0.81	VCAM1 (0.51)	VCAM1GRM8GRM6GRM4MAPT
	SCHEMBL257727	0.80	VCAM1 (0.56)	VCAM1MAPTMEN1KMT2ACYP1A2
	SCHEMBL21064544	0.80	VCAM1 (0.56)	VCAM1MAPTMEN1KMT2ACYP1A2
	SCHEMBL16654006	0.79	ALDH1A1 (0.53)	VCAM1GRM8GRM6GRM4MAPT
	SCHEMBL11315745	0.79	PDK1 (0.51)	GRM8GRM6GRM4MAPTMEN1
	SCHEMBL7531523	0.79	MAPK1 (0.56)	GRM8GRM6GRM4MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.