SCHEMBL17263862

SCHEMBL17263862

CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5O

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 0.66
OPRD1 P41143 6/20 0.66
OPRK1 P41145 5/20 0.66
MRGPRX2 Q96LB1 2/20 0.66
SLC22A1 O15245 1/20 0.66
ADRA2A P08913 1/20 0.66
ARRB1 P49407 1/20 0.66
SIGMAR1 Q99720 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL918542 0.86 OPRM1 (0.67) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
SCHEMBL18867761 0.80 OPRM1 (0.66) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
SCHEMBL12283963 0.80 OPRM1 (0.66) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
SCHEMBL13151540 0.80 OPRM1 (0.66) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
SCHEMBL19880922 0.80 OPRM1 (0.66) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
Morphine SCHEMBL24599520 0.79 OPRD1 (1.00) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
Morphine SCHEMBL13154676 0.79 OPRD1 (1.00) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
Morphine SCHEMBL13696339 0.79 OPRD1 (1.00) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
Morphine SCHEMBL10820235 0.79 OPRD1 (1.00) OPRM1OPRD1OPRK1MRGPRX2SLC22A1
Morphine SCHEMBL8049464 0.79 OPRD1 (1.00) OPRM1OPRD1OPRK1MRGPRX2SLC22A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3424547-B1 PACKAGING SYSTEM FOR OXYGEN-SENSITIVE DRUGS FRESENIUS KABI AUSTRIA GMBH (AT) 2026-02-11 EP disclosed
US-20200345720-A1 MORPHINE FORMULATIONS FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2020-11-05 US disclosed
EP-3424547-A1 PACKAGING SYSTEM FOR OXYGEN-SENSITIVE DRUGS Fresenius Kabi Austria GmbH (AT) 2019-01-09 EP disclosed
EP-2968132-B1 INJECTABLE MORPHINE FORMULATIONS FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2017-09-13 EP disclosed
EP-3143988-A1 INJECTABLE MORPHINE FORMULATIONS Fresenius Kabi Deutschland GmbH (DE) 2017-03-22 EP disclosed
US-9192608-B2 Morphine formulations BECTON DICKINSON FRANCE S.A.S. (FR) 2015-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200345720-A1 MORPHINE FORMULATIONS OPRM1, OPRK1, OPRD1 OPRM1 1/4885OPRD1 3/4885OPRK1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.