Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSK | P41240 | 1/20 | 0.50 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 6/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18347157 | 0.81 | TAAR1 (0.50) | SLC7A5 | |
| SCHEMBL18647241 | 0.77 | CSK (0.54) | CSKF11LPLLIPGKDM4E | |
| SCHEMBL10201264 | 0.77 | AGXT (0.39) | CA1CA2SLC6A4 | |
| SCHEMBL15802699 | 0.77 | EPHX1 (0.56) | SLC6A4SLC7A5 | |
| SCHEMBL12015253 | 0.73 | SLC6A4 (0.32) | SLC6A4 | |
| SCHEMBL14666765 | 0.72 | ITGB3 (0.35) | SLC6A4 | |
| SCHEMBL14666766 | 0.72 | NQO1 (0.45) | CA1CA2 | |
| SCHEMBL21350258 | 0.71 | PTPN1 (0.35) | SLC6A4 | |
| SCHEMBL24861513 | 0.71 | CSK (0.54) | CSKF11LPLLIPGCA1 | |
| SCHEMBL22403249 | 0.71 | CSK (0.54) | CSKF11LPLLIPGCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065993-A1 | RAPID AND EFFICIENT BIOORTHOGONAL LIGATION REACTION AND BORON-CONTAINING HETEROCYCLES USEFUL IN CONJUNCTION THEREWITH | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2018-03-08 | — | — | US | disclosed |
| US-9758533-B2 | Rapid and efficient bioorthogonal ligation reaction and boron-containing heterocycles useful in conjunction therewith | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-09-12 | — | — | US | disclosed |
| US-20150329568-A1 | RAPID AND EFFICIENT BIOORTHOGONAL LIGATION REACTION AND BORON-CONTAINING HETEROCYCLES USEFUL IN CONJUNCTION THEREWITH | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065993-A1 | RAPID AND EFFICIENT BIOORTHOGONAL LIGATION REACTION AND BORON-CONTAINING HETEROCYCLES USEFUL IN CONJUNCTION THEREWITH | BLVRB, BTD, BCAT1 | CSK 527/4885F11 1383/4885LPL 4610/4885 |
| US-20150329568-A1 | RAPID AND EFFICIENT BIOORTHOGONAL LIGATION REACTION AND BORON-CONTAINING HETEROCYCLES USEFUL IN CONJUNCTION THEREWITH | BLVRB, BCAT1, BCAT2 | CSK 410/4885F11 1316/4885LPL 4604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.