SCHEMBL1726459

SCHEMBL1726459

C=C(C)C(=O)Nc1ccc(B(O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.59
TRPV1 Q8NER1 6/20 0.51
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 3/20 0.44
POLB P06746 2/20 0.44
RECQL P46063 1/20 0.44
BLM P54132 1/20 0.44
BAZ1A Q9NRL2 1/20 0.43
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
HTT P42858 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CA2 P00918 1/20 0.39
LPL P06858 1/20 0.39
LIPG Q9Y5X9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439393 0.86 RXFP1 (0.74) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL18989422 0.83 RXFP1 (0.43) RXFP1TRPV1TDP1L3MBTL1POLB
SCHEMBL9162 0.80 SMN1; SMN2 (0.61) TRPV1TDP1L3MBTL1POLBKDM4E
SCHEMBL17084525 0.80 RXFP1 (0.67) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL390106 0.80 TDP1 (0.64) RXFP1TRPV1TDP1L3MBTL1POLB
SCHEMBL124216 0.79 RXFP1 (0.65) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL959539 0.79 RXFP1 (0.65) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL8164496 0.77 RXFP1 (0.62) RXFP1TRPV1TDP1L3MBTL1POLB
Hydrochloric Acid SCHEMBL7460090 0.77 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL5071228 0.77 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11035080-B2 Boronic acid containing polymers for papermaking process ECOLAB USA INC. (US) 2021-06-15 US claimed
EP-3390715-B1 BORONIC ACID CONTAINING POLYMERS FOR PAPERMAKING PROCESS ECOLAB USA INC (US) 2020-12-02 EP claimed
US-20180327972-A1 BORONIC ACID CONTAINING POLYMERS FOR PAPERMAKING PROCESS ECOLAB USA INC. (US) 2018-11-15 US claimed
EP-3390715-A1 BORONIC ACID CONTAINING POLYMERS FOR PAPERMAKING PROCESS Ecolab USA Inc. (US) 2018-10-24 EP claimed
WO-2017106310-A1 BORONIC ACID CONTAINING POLYMERS FOR PAPERMAKING PROCESS ECOLAB USA INC. (US) 2017-06-22 WO claimed
US-20120097540-A1 MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS JAMES TONY DAVID (GB) 2012-04-26 US claimed
US-11035080-B2 Boronic acid containing polymers for papermaking process ECOLAB USA INC. (US) 2021-06-15 US disclosed
US-10765110-B2 Agent for preserving biological component Tabata, Yasuhiko (JP) 2020-09-08 US disclosed
US-20170311586-A1 AGENT FOR PRESERVING BIOLOGICAL COMPONENT, AND METHOD FOR RECOVERING BIOLOGICAL COMPONENT Tabata, Yasuhiko (JP) 2017-11-02 US disclosed
EP-3219787-A1 AGENT FOR PRESERVING BIOLOGICAL COMPONENT, AND METHOD FOR RECOVERING BIOLOGICAL COMPONENT Denka Company Limited (JP) 2017-09-20 EP disclosed
US-20120097540-A1 MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS JAMES TONY DAVID (GB) 2012-04-26 US disclosed
EP-2344885-A2 MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS The University of Bath (GB) 2011-07-20 EP disclosed
WO-2010041037-A2 MATERIALS AND METHODS FOR RESOLVING POLYHYDRIC SPECIES BY ELECTROPHORESIS THE UNIVERSITY OF BATH (GB) 2010-04-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170311586-A1 AGENT FOR PRESERVING BIOLOGICAL COMPONENT, AND METHOD FOR RECOVERING BIOLOGICAL COMPONENT CD44, HPSE, PLOD3 RXFP1 1729/4885TRPV1 3934/4885TDP1 1243/4885
US-10765110-B2 Agent for preserving biological component CD44, MUC1, PLOD3 RXFP1 2283/4885TRPV1 3855/4885TDP1 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.