SCHEMBL1726460

SCHEMBL1726460

C=CCOC(=O)C(C=CC#N)=CC=CC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
CYP3A4 P08684 1/20 0.31
PTP4A3 O75365 1/20 0.31
PTP4A1 Q93096 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL327788 0.88 CYP3A4 (0.38) MAPTCYP3A4PTP4A3PTP4A1HCAR2
SCHEMBL8002027 0.82 HCAR2 (0.47) MAPTHCAR2
SCHEMBL9547843 0.81 CASP1 (0.42) MAPTCYP3A4APP
SCHEMBL2499451 0.78 HCAR2 (0.53) MAPTHCAR2APP
SCHEMBL7125436 0.77 ALDH1A1 (0.45) MAPTCACNA1BAPBA1PTP4A3PTP4A1
SCHEMBL30941 0.76 MAPT (0.52) MAPTCACNA1BAPBA1CYP3A4PTP4A3
SCHEMBL2086750 0.76 MAPT (0.52) MAPTCACNA1BAPBA1CYP3A4PTP4A3
SCHEMBL4559229 0.76 CASP1 (0.44) MAPTCYP3A4PTP4A3PTP4A1APP
SCHEMBL305584 0.74 TSHR (0.32) MAPT
SCHEMBL9716477 0.74 HDAC3 (0.46) MAPTCYP3A4HCAR2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7579128-B2 Toner compositions including styrene containing external additives XEROX CORPORATION (US) 2009-08-25 US claimed
US-20080241724-A1 TONER COMPOSITIONS INCLUDING STYRENE CONTAINING EXTERNAL ADDITIVES XEROX CORPORATION (US) 2008-10-02 US claimed
CN-113376980-B Titanium dioxide-free toner additive formulation with crosslinked organic polymer additive 施乐公司 2023-12-05 CN disclosed
CN-116804836-A Toner containing charge control agent 施乐公司 2023-09-26 CN disclosed
CN-116774541-A Toner comprising reactive charge control agent 施乐公司 2023-09-19 CN disclosed
CN-116774542-A Toner containing charge control agent 施乐公司 2023-09-19 CN disclosed
CN-108153121-B Metal toner comprising metal integrated particles 施乐公司 2023-06-20 CN disclosed
CN-115677911-A Organic additives and compositions containing organic additives 施乐公司 2023-02-03 CN disclosed
US-11380888-B2 Electrode and lithium secondary battery comprising same LG ENERGY SOLUTION, LTD. (KR) 2022-07-05 US disclosed
CN-114265290-A Textile custom printed with antimicrobial nanoparticles 施乐公司 2022-04-01 CN disclosed
CN-109964344-B Electrode and lithium secondary battery comprising the same 株式会社LG化学 2021-12-21 CN disclosed
US-20140272703-A1 TRIBOELECTRIC CHARGE CONTROL OF TONER THROUGH MONOMER RATIO OF SHELL LATEX XEROX CORPORATION (US) 2014-09-18 US disclosed
CN-102413948-A Electronic devices comprising structured organic films (SOF) XEROX CORP 2012-04-11 CN disclosed
CN-102341187-A Process for preparing structured organic films (SOFs) via a pre-sof XEROX CORP 2012-02-01 CN disclosed
CN-102341186-A Electronic devices comprising structured organic films XEROX CORP 2012-02-01 CN disclosed
EP-2403858-A1 STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY Xerox Corporation (US) 2012-01-11 EP disclosed
WO-2010102036-A1 STRUCTURED ORGANIC FILMS HAVING AN ADDED FUNCTIONALITY XEROX CORPORATION (US) 2010-09-10 WO disclosed
US-7579128-B2 Toner compositions including styrene containing external additives XEROX CORPORATION (US) 2009-08-25 US disclosed
US-20080241724-A1 TONER COMPOSITIONS INCLUDING STYRENE CONTAINING EXTERNAL ADDITIVES XEROX CORPORATION (US) 2008-10-02 US disclosed
US-20060269858-A1 Toner compositions including styrene containing external additives XEROX CORPORATION (US) 2006-11-30 US disclosed