SCHEMBL17265383

SCHEMBL17265383

c1ccc(-c2cc3c4cccc5c4c(cc3c3ccccc23)-c2ccc(-c3c4ccccc4cc4ccccc34)cc2O5)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.38
GPR84 Q9NQS5 10/20 0.37
KDM4E B2RXH2 3/20 0.37
MAPK1 P28482 2/20 0.37
ATM Q13315 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.35
HPGD P15428 2/20 0.35
MAPT P10636 1/20 0.35
MPI P34949 1/20 0.35
TSHR P16473 1/20 0.34
CASP1 P29466 1/20 0.34
HIF1A Q16665 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CES1 P23141 1/20 0.33
RECQL P46063 1/20 0.32
HSD17B1 P14061 1/20 0.32
HSD17B2 P37059 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17265399 0.92 GPR84 (0.37) ALOX5GPR84KDM4EMAPK1ATM
SCHEMBL17265389 0.90 ALDH1A1 (0.42) ALOX5GPR84KDM4EMAPK1ATM
SCHEMBL17265414 0.90 GPR84 (0.39) ALOX5GPR84KDM4EMAPK1ATM
SCHEMBL17265409 0.88 ALOX5 (0.34) ALOX5KDM4EMAPK1ATMALDH1A1
SCHEMBL17265382 0.87 KDM4E (0.36) GPR84KDM4EMAPK1ATMMEN1
SCHEMBL17265410 0.84 KDM4E (0.32) ALOX5KDM4EMAPK1ATM
SCHEMBL16376406 0.83 KDM4E (0.40) ALOX5GPR84KDM4EMAPK1ATM
SCHEMBL17265392 0.83 KDM4E (0.37) GPR84KDM4EMAPK1ATMMEN1
SCHEMBL19678365 0.82 HPGD (0.42) GPR84KDM4EMAPK1ATMMEN1
SCHEMBL19600404 0.82 KDM4E (0.40) ALOX5GPR84KDM4EMAPK1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-9711736-B2 Condensed cyclic compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed
US-20150333268-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2015-11-19 US disclosed