Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28451038 | 0.77 | KDM4E (0.54) | GAAPOLBKDM4EMEN1MAPT | |
| SCHEMBL28891879 | 0.72 | MAPT (0.55) | GAAPOLBKDM4EMEN1MAPT | |
| SCHEMBL9952093 | 0.72 | KDM4E (0.51) | GAAPOLBKDM4EMEN1MAPT | |
| SCHEMBL6680 | 0.71 | POLB (0.42) | GAAPOLBKDM4EMEN1MAPT | |
| SCHEMBL25275004 | 0.71 | L3MBTL1 (0.58) | GAAPOLBKDM4EMEN1MAPT | |
| SCHEMBL28023340 | 0.71 | GAA (0.58) | GAAPOLBKDM4EMEN1MAPT | |
| SCHEMBL25278077 | 0.71 | MAPT (0.58) | GAAPOLBKDM4EMEN1MAPT | |
| SCHEMBL11585789 | 0.71 | MEN1 (0.50) | MEN1KMT2ABCHELMNAHTT | |
| SCHEMBL5446365 | 0.71 | HPGD (0.46) | POLBKDM4EMAPTKMT2ALMNA | |
| SCHEMBL5702222 | 0.71 | KMT2A (0.54) | GAAPOLBKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111484438-B | Polysubstituted indole derivative and metal catalysis preparation method thereof | 湖北科技学院 | 2023-02-03 | — | — | CN | disclosed |
| CN-111484438-A | Polysubstituted indole derivative and metal catalysis preparation method thereof | 湖北科技学院 | 2020-08-04 | — | — | CN | disclosed |