Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1462886 | 0.96 | SLC6A3 (0.40) | SLC6A3KCNH2TAAR1SMARCA2SMARCA4 | |
| SCHEMBL1725098 | 0.82 | SLC6A3 (0.43) | SLC6A3KCNH2TAAR1TAS1R3TAS1R1 | |
| SCHEMBL1727518 | 0.82 | SLC6A3 (0.45) | SLC6A3KCNH2TAAR1TAS1R3TAS1R1 | |
| SCHEMBL1462914 | 0.81 | GPR119 (0.42) | MAPTMEN1KMT2A | |
| SCHEMBL2681577 | 0.81 | MEN1 (0.44) | SLC6A3KCNH2TAAR1TAS1R3TAS1R1 | |
| Trifluoroacetic Acid SCHEMBL1463150 | 0.81 | SLC6A3 (0.40) | SLC6A3KCNH2TAAR1TAS1R3TAS1R1 | |
| SCHEMBL1727318 | 0.79 | MCHR1 (0.44) | GSK3B | |
| SCHEMBL433524 | 0.78 | RAF1 (0.43) | SLC6A3KCNH2TAAR1 | |
| SCHEMBL1420945 | 0.78 | MCHR1 (0.40) | MEN1KMT2A | |
| SCHEMBL12153456 | 0.78 | GSK3B (0.39) | MAPTGSK3AGSK3BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10034476-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2018-07-31 | — | — | US | disclosed |
| US-20170347650-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-07 | — | — | US | disclosed |
| US-9808006-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-11-07 | — | — | US | disclosed |
| US-20130317062-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-11-28 | — | — | US | disclosed |
| US-8518971-B2 | Insecticidal phenyl- or pyridyl-piperdine compounds | SYNGENTA CROP PROTECTION, INC. (US) | 2013-08-27 | — | — | US | disclosed |
| WO-2012037282-A3 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | NOVOMER, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| EP-2324010-B1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERIDINE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-11-30 | — | — | EP | disclosed |
| US-20110136866-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERDINE COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10034476-B2 | Insecticidal phenyl-or pyridyl-piperdine compounds | ACHE, CHRM1, CHRM2 | SLC6A3 4236/4885KCNH2 457/4885TAAR1 55/4885 |
| US-20130317062-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | SLC6A3 4236/4885KCNH2 457/4885TAAR1 55/4885 |
| US-20110136866-A1 | INSECTICIDAL PHENYL- OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | SLC6A3 4116/4885KCNH2 442/4885TAAR1 63/4885 |
| US-20170347650-A1 | INSECTICIDAL PHENYL-OR PYRIDYL-PIPERDINE COMPOUNDS | ACHE, CHRM1, CHRM2 | SLC6A3 4236/4885KCNH2 457/4885TAAR1 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.