Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20680748 | 0.88 | P2RX7 (0.37) | PTPN11MAPK14P2RX7HSD11B1CYP3A4 | |
| SCHEMBL20680788 | 0.85 | SPR (0.43) | PTPN11P2RX7HSD11B1MAPTSPR | |
| SCHEMBL20698006 | 0.84 | P2RX7 (0.37) | PTPN11P2RX7HSD11B1CYP3A4HTT | |
| SCHEMBL20698279 | 0.84 | BCL2L11 (0.43) | MAPK14P2RX7HSD11B1CYP3A4MAPT | |
| SCHEMBL17674744 | 0.78 | MAPK14 (0.50) | MAPK14CYP3A4MAPTHTTCYP1A2 | |
| SCHEMBL20698182 | 0.77 | P2RX7 (0.35) | PTPN11P2RX7HSD11B1CYP3A4CYP1A2 | |
| SCHEMBL14990081 | 0.76 | MAPK14 (0.45) | MAPK14P2RX7HSD11B1CYP3A4MAPT | |
| SCHEMBL17514923 | 0.76 | HSD11B1 (0.47) | PTPN11P2RX7HSD11B1CYP3A4SPR | |
| SCHEMBL20698175 | 0.76 | HSD11B1 (0.49) | PTPN11P2RX7HSD11B1 | |
| SCHEMBL28835084 | 0.75 | HSD11B1 (0.44) | PTPN11P2RX7HSD11B1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10448639-B2 | Fungicidal pyrazoles | FMC CORPORATION (US) | 2019-10-22 | — | — | US | disclosed |
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2017-08-10 | — | — | US | disclosed |
| US-9655361-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-05-23 | — | — | US | disclosed |
| EP-2966063-A1 | FUNGICIDAL PYRAZOLES | E. I. du Pont de Nemours and Company (US) | 2016-01-13 | — | — | EP | disclosed |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | FMC CORPORATION | 2015-08-20 | — | — | US | disclosed |
| US-9062005-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-06-23 | — | — | US | disclosed |
| EP-2403834-A1 | Fungicidal pyrazoles | E. I. du Pont de Nemours and Company (US) | 2012-01-11 | — | — | EP | disclosed |
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | E.I. DU PONT NEMOURS AND COMPANY (US) | 2011-12-29 | — | — | US | disclosed |
| WO-2010101973-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319430-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | PTPN11 1104/4885MAPK14 2009/4885P2RX7 1017/4885 |
| US-10448639-B2 | Fungicidal pyrazoles | CBR3, CBR1, CYP2S1 | PTPN11 1104/4885MAPK14 2009/4885P2RX7 1017/4885 |
| US-20150230467-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | PTPN11 1104/4885MAPK14 2009/4885P2RX7 1017/4885 |
| US-20170223959-A1 | FUNGICIDAL PYRAZOLES | CBR3, CBR1, CYP2S1 | PTPN11 1104/4885MAPK14 2009/4885P2RX7 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.