Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 4/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.60 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.60 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.60 |
| ▸ | HMGCR | P04035 | 6/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | RHOC | P08134 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.59 |
| ▸ | PDE6D | O43924 | 4/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20130319 | 0.95 | SLCO1B1 (0.59) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL14526747 | 0.87 | HMGCR (0.64) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL12285672 | 0.81 | HMGCR (0.83) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL12558520 | 0.81 | HMGCR (0.83) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL28552009 | 0.81 | HMGCR (0.83) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL2539128 | 0.80 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL2539127 | 0.80 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL2539132 | 0.80 | SLCO1B1 (0.66) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL14414021 | 0.80 | HMGCR (0.62) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 | |
| SCHEMBL9366015 | 0.79 | HMGCR (0.72) | SLCO1B1ABCB11ABCC3ABCC4SLCO1B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9844599-B2 | Nitric oxide releasing produgs of therapeutic agents | SATYAM APPARAO (IN) | 2017-12-19 | — | — | US | disclosed |
| US-20150328323-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | SATYAM APPARAO (IN) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328323-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | NOS2, NOS1, PTGIS | SLCO1B1 1304/4885ABCB11 1174/4885ABCC3 1387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.