Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 8/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CBFB | Q13951 | 4/20 | 0.34 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | FOXO1 | Q12778 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17268673 | 0.88 | ALPL (0.40) | CBFBFOXO1 | |
| SCHEMBL17268693 | 0.87 | CBFB (0.39) | NPBWR1CBFBFOXO1 | |
| SCHEMBL17268720 | 0.86 | MAPT (0.39) | CBFBFOXO1 | |
| SCHEMBL17268676 | 0.86 | AMY1A (0.38) | CBFBFOXO1 | |
| SCHEMBL17268691 | 0.85 | NPBWR1 (0.45) | NPBWR1DGAT1KCNH2CBFBPDPK1 | |
| SCHEMBL17268664 | 0.84 | CBFB (0.45) | CBFBFOXO1 | |
| SCHEMBL17268715 | 0.83 | CBFB (0.35) | NPBWR1CBFBFOXO1 | |
| SCHEMBL17268683 | 0.83 | AMY1A (0.49) | CBFBPDPK1FOXO1 | |
| SCHEMBL17268690 | 0.82 | CBFB (0.39) | CBFBFOXO1 | |
| SCHEMBL17268755 | 0.82 | AMY1A (0.42) | CBFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951049-B2 | Pyrazole linked benzimidazole conjugates and a process for preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150329527-A1 | PYRAZOLE LINKED BENZIMIDAZOLE CONJUGATES AND A PROCESS FOR PREPARATION THEREOF | BRDT, MCL1, MGST3 | NPBWR1 3574/4885DGAT1 2730/4885KCNH2 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.