Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 7/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | CBLB | Q13191 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726319 | 0.86 | CYP11B2 (0.58) | FFAR4CYP11B2ALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL1721039 | 0.84 | FFAR4 (0.62) | FFAR4CYP11B2ALDH1A1UGCGCYP11B1 | |
| SCHEMBL1721366 | 0.69 | FFAR4 (0.68) | FFAR4CYP11B2ALDH1A1CYP11B1LMNA | |
| SCHEMBL1720348 | 0.67 | FFAR4 (0.56) | FFAR4CYP11B2ALDH1A1CYP11B1LMNA | |
| SCHEMBL11483460 | 0.67 | LMNA (0.53) | FFAR4CYP11B2ALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL10547527 | 0.66 | LMNA (0.50) | FFAR4CYP11B2ALDH1A1SMN1; SMN2CYP11B1 | |
| SCHEMBL1721253 | 0.66 | FFAR4 (0.60) | FFAR4CYP11B2ALDH1A1CYP11B1LMNA | |
| SCHEMBL19967147 | 0.65 | CYP11B2 (0.58) | FFAR4CYP11B2UGCGCYP11B1LMNA | |
| SCHEMBL19965112 | 0.65 | FFAR4 (0.36) | FFAR4CYP11B2ALDH1A1SMN1; SMN2UGCG | |
| SCHEMBL13186445 | 0.65 | FFAR4 (0.79) | FFAR4LMNATDP1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406248-A1 | NOVEL ISOINDOLIN-1-ONE DERIVATIVE | MSD K.K. (JP) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010104195-A1 | NOVEL ISOINDOLIN-1-ONE DERIVATIVE | BANYU PHARMACEUTICAL CO.,LTD. (JP) | 2010-09-16 | — | — | WO | disclosed |