SCHEMBL1721039

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1721366	0.85	FFAR4 (0.68)	FFAR4GRM5CYP11B2LMNATDP1
	SCHEMBL1727308	0.84	FFAR4 (0.45)	FFAR4GRM5CYP11B2LMNATDP1
	SCHEMBL1720348	0.83	FFAR4 (0.56)	FFAR4GRM5CYP11B2LMNATDP1
	SCHEMBL1721253	0.82	FFAR4 (0.60)	FFAR4GRM5CYP11B2LMNATDP1
	SCHEMBL13186445	0.78	FFAR4 (0.79)	FFAR4GRM5LMNATDP1HTT
	SCHEMBL1724866	0.77	FFAR4 (1.00)	FFAR4GRM5LMNATDP1HTT
	SCHEMBL13186545	0.71	FFAR4 (0.67)	FFAR4GRM5LMNATDP1FFAR1
	SCHEMBL1726319	0.70	CYP11B2 (0.58)	FFAR4CYP11B2LMNAHTTCYP11B1
	SCHEMBL1720587	0.70	NPC1 (0.49)	FFAR4CYP11B2LMNAHTTFFAR1
	SCHEMBL2432363	0.68	FFAR4 (0.51)	FFAR4GRM5LMNATDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.