Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.45 |
| ▸ | HTR3B | O95264 | 2/20 | 0.45 |
| ▸ | HTR3A | P46098 | 2/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2812938 | 0.86 | ALDH1A1 (0.57) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28382188 | 0.74 | PARP1 (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29111944 | 0.73 | HPGD (0.47) | ALDH1A1NPC1RAB9ABCL2A1PARP1 | |
| SCHEMBL70822 | 0.73 | — | — | |
| SCHEMBL6203985 | 0.73 | — | — | |
| SCHEMBL29635640 | 0.73 | — | — | |
| SCHEMBL10940472 | 0.71 | HSD17B2 (0.54) | HSD17B1HSD17B2 | |
| SCHEMBL29111930 | 0.71 | ALDH1A1 (0.68) | ALDH1A1NPC1RAB9AMEN1GAA | |
| SCHEMBL30743887 | 0.71 | MTNR1A (0.50) | PARP1HSD17B1HSD17B2TP53HTT | |
| SCHEMBL1794813 | 0.71 | ACHE (0.54) | ALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9387186-B2 | Thiourea derivatives | CHOUDHARY MUHAMMAD IQBAL (PK) | 2016-07-12 | — | — | US | claimed |
| US-20150335594-A1 | THIOUREA DERIVATIVES | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-11-26 | — | — | US | claimed |
| US-9387186-B2 | Thiourea derivatives | CHOUDHARY MUHAMMAD IQBAL (PK) | 2016-07-12 | — | — | US | disclosed |
| US-9387186-B2 | Thiourea derivatives | CHOUDHARY MUHAMMAD IQBAL (PK) | 2016-07-12 | — | — | US | disclosed |
| US-20150335594-A1 | THIOUREA DERIVATIVES | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-11-26 | — | — | US | disclosed |
| US-20150335594-A1 | THIOUREA DERIVATIVES | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150335594-A1 | THIOUREA DERIVATIVES | TPMT, TST, NSUN3 | HTR3E 2236/4885HTR3B 2089/4885HTR3A 1972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.