Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP1 | P63208 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729627 | 0.86 | CHRM4 (0.43) | HRH3CHRM4CHRM2CHRM1ACACB | |
| SCHEMBL3269876 | 0.84 | HRH3 (0.40) | HRH3CHRM4TRPV3ACACBTGM2 | |
| SCHEMBL1728425 | 0.84 | HTR1A (0.51) | CHRM4ACACBCKS1BSKP1SKP2 | |
| SCHEMBL240061 | 0.83 | HRH3 (0.39) | HRH3CHRM4TRPV3ACACBCKS1B | |
| SCHEMBL1728737 | 0.83 | HSD11B1 (0.49) | CHRM4CHRM2 | |
| SCHEMBL1729311 | 0.80 | HTR1A (0.46) | CHRM4FFAR4CHRM2ACACB | |
| SCHEMBL5777613 | 0.80 | HRH3 (0.44) | HRH3FFAR4TRPV3ACACB | |
| SCHEMBL14797306 | 0.79 | HSD11B1 (0.44) | CHRM4FFAR4ACACBCKS1BSKP1 | |
| SCHEMBL1728924 | 0.79 | CNR1 (0.47) | CHRM4CKS1BSKP1SKP2TGM2 | |
| SCHEMBL1728880 | 0.78 | CHRM4 (0.49) | CHRM4CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | disclosed |
| CN-1812980-B | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their use as pharmaceuticals | SANOFI AVENTIS | 2011-04-06 | — | — | CN | disclosed |
| CN-101712660-A | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their therapeutic use | SANOFI AVENTIS | 2010-05-26 | — | — | CN | disclosed |
| CN-1812980-A | Piperidinyl-and piperazinyl-alkylcarbamate derivatives, their preparation and their therapeutic use | SANOFI AVENTIS (FR) | 2006-08-02 | — | — | CN | disclosed |
| EP-1633735-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004099176-A1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2004-11-18 | — | — | WO | disclosed |