Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.43 |
| ▸ | CKS1B | P61024 | 3/20 | 0.43 |
| ▸ | SKP1 | P63208 | 3/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727464 | 0.86 | HRH3 (0.42) | CHRM4CKS1BSKP1SKP2CHRM2 | |
| SCHEMBL1728425 | 0.85 | HTR1A (0.51) | CHRM4CKS1BSKP1SKP2PDE10A | |
| SCHEMBL1728737 | 0.83 | HSD11B1 (0.49) | CHRM4CHRM2 | |
| SCHEMBL3265488 | 0.83 | FAAH (0.40) | CHRM4CKS1BSKP1SKP2PKM | |
| SCHEMBL1729311 | 0.81 | HTR1A (0.46) | CHRM4CHRM2ACACB | |
| SCHEMBL1728924 | 0.80 | CNR1 (0.47) | CHRM4CKS1BSKP1SKP2 | |
| SCHEMBL1727908 | 0.79 | FFAR4 (0.47) | CHRM4ACACB | |
| SCHEMBL1710939 | 0.78 | CYP11B2 (0.45) | CHRM4CKS1BSKP1SKP2CHRM2 | |
| SCHEMBL1728810 | 0.78 | CKS1B (0.38) | CKS1BSKP1SKP2PKMAOC3 | |
| SCHEMBL1710866 | 0.78 | SIRT2 (0.49) | CKS1BSKP1SKP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |