Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727908 | 0.95 | FFAR4 (0.47) | HTR1ADRD2DRD4FFAR4CHRM4 | |
| SCHEMBL1728737 | 0.86 | HSD11B1 (0.49) | CHRM4HSD11B1ACHECHRM2 | |
| SCHEMBL1728425 | 0.85 | HTR1A (0.51) | HTR1ADRD2DRD4CHRM4ACACB | |
| SCHEMBL1728924 | 0.85 | CNR1 (0.47) | CHRM4ACHE | |
| SCHEMBL3266800 | 0.81 | ACACB (0.40) | HTR1ADRD2DRD4FFAR4CHRM4 | |
| SCHEMBL14796921 | 0.81 | CHRM4 (0.48) | CHRM4ACHE | |
| SCHEMBL1710939 | 0.81 | CYP11B2 (0.45) | CHRM4ACHECHRM2 | |
| SCHEMBL1710740 | 0.81 | CHRM4 (0.48) | HTR1ADRD2DRD4FFAR4CHRM4 | |
| SCHEMBL1729627 | 0.81 | CHRM4 (0.43) | CHRM4ACACBCHRM2 | |
| SCHEMBL14797005 | 0.80 | FFAR4 (0.46) | FFAR4CHRM4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |