Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 7/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728878 | 0.91 | AOC3 (0.46) | DGAT1KCNH2MCHR1KDM4EABL1 | |
| SCHEMBL1727662 | 0.83 | HTR1A (0.43) | DGAT1ADORA2AKCNH2MCHR1KDM4E | |
| SCHEMBL1727925 | 0.82 | AKR1C3 (0.44) | DGAT1MCHR1KDM4EABL1LMNA | |
| SCHEMBL1727605 | 0.82 | DGAT1 (0.44) | DGAT1ADORA2AKCNH2MCHR1KDM4E | |
| SCHEMBL1729052 | 0.81 | NPC1 (0.43) | HTR1ADRD4HTR2ADRD3L3MBTL1 | |
| SCHEMBL1730021 | 0.78 | HTR1A (0.41) | KDM4EHTR1AAOC3OPRM1 | |
| SCHEMBL14796958 | 0.78 | MCHR1 (0.56) | KCNH2MCHR1SCD | |
| SCHEMBL1729788 | 0.74 | TDO2 (0.53) | DGAT1ADORA2AKCNH2MCHR1SCD | |
| SCHEMBL1729030 | 0.73 | CKS1B (0.55) | DGAT1ADORA2AKCNH2SCDHTR1A | |
| SCHEMBL3265677 | 0.73 | TDO2 (0.51) | DGAT1ADORA2AKCNH2SCDTDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |