Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 7/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729059 | 0.91 | DGAT1 (0.41) | DGAT1ADORA2AKCNH2MCHR1L3MBTL1 | |
| SCHEMBL1730188 | 0.84 | AKR1C3 (0.39) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL1730161 | 0.84 | DEGS1 (0.43) | HTR1ADRD4HTR2ADRD3DGAT1 | |
| SCHEMBL1729687 | 0.84 | LMNA (0.53) | DPP4DPP8DPP9DPP7HRH3 | |
| SCHEMBL1728785 | 0.83 | HTR1A (0.41) | HTR1ADRD4HTR2ADRD3DPP4 | |
| SCHEMBL1727973 | 0.83 | HRH3 (0.44) | HRH3 | |
| SCHEMBL1727913 | 0.81 | HRH3 (0.38) | HRH3 | |
| SCHEMBL1728838 | 0.81 | DPP4 (0.40) | HTR1ADPP4DPP8DPP9DPP7 | |
| SCHEMBL1730251 | 0.79 | DPP4 (0.42) | DPP4DPP8DPP9DPP7DGAT1 | |
| SCHEMBL1729774 | 0.78 | LMNA (0.36) | DPP4DPP8DPP9DPP7SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |