Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MMP7 | P09237 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1730161 | 0.88 | DEGS1 (0.43) | PANK3PDE10AKDM4EDEGS1 | |
| SCHEMBL1727973 | 0.86 | HRH3 (0.44) | PPARGPPARAKMT2ALMNAMEN1 | |
| SCHEMBL1729687 | 0.85 | LMNA (0.53) | KMT2AKDM4EABL1LMNADPP4 | |
| SCHEMBL1727604 | 0.84 | HTR1A (0.41) | DPP4DPP8DPP9DPP7L3MBTL1 | |
| SCHEMBL1729059 | 0.84 | DGAT1 (0.41) | KDM4EL3MBTL1DEGS1 | |
| SCHEMBL1727913 | 0.84 | HRH3 (0.38) | PANK3LMNAHRH3 | |
| SCHEMBL1730251 | 0.82 | DPP4 (0.42) | DPP4DPP8DPP9DPP7CXCR3 | |
| SCHEMBL1727545 | 0.82 | GRIN2D (0.36) | KMT2AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1729774 | 0.81 | LMNA (0.36) | KMT2AKDM4ELMNADPP4DPP8 | |
| SCHEMBL1730303 | 0.81 | LMNA (0.36) | PANK3KMT2ALMNADPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |