⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL506475 | 0.76 | — | — | |
| SCHEMBL13453130 | 0.76 | — | — | |
| SCHEMBL838012 | 0.70 | — | — | |
| SCHEMBL3482289 | 0.70 | — | — | |
| SCHEMBL12907186 | 0.67 | — | — | |
| SCHEMBL29804 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL838349 | 0.67 | — | — | |
| SCHEMBL1107768 | 0.64 | — | — | |
| SCHEMBL2098831 | 0.64 | — | — | |
| SCHEMBL28595196 | 0.64 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1149086-B1 | NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES | LEK TOVARNA FARMACEVTSKIH (SI) | 2004-05-12 | — | — | EP | claimed |
| US-6509479-B1 | To produce simvastatin | LEK PHARMACEUTICALS D.D. (SI) | 2003-01-21 | — | — | US | claimed |
| EP-1149086-A1 | NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES | Lek Pharmaceutical and Chemical Co. D.D. (SI) | 2001-10-31 | — | — | EP | claimed |
| WO-2000046217-A1 | NOVEL PROCESS FOR THE REMOVAL OF A SILYLOXY PROTECTING GROUP FROM 4-SILYLOXY-TETRAHYDRO-PYRAN-2-ONES | LEK PHARMACEUTICALS AND CHEMICAL COMPANY D.D. (SI) | 2000-08-10 | — | — | WO | claimed |
| US-5650523-A | REACTION IN SOLVENTS TO FORM HYDROXY GROUPS | MERCK & CO., INC. (US) | 1997-07-22 | — | — | US | claimed |
| EP-0444888-B1 | Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one | MERCK & CO INC (US) | 1995-02-08 | — | — | EP | claimed |
| EP-0444888-A1 | Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one | MERCK & CO. INC. (US) | 1991-09-04 | — | — | EP | claimed |
| US-20200362067-A1 | SILOXANE COMPOUND AND A METHOD FOR PREPARING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-11-19 | — | — | US | disclosed |
| EP-3719025-A1 | SILOXANE COMPOUND AND METHOD FOR PRODUCING SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 2020-10-07 | — | — | EP | disclosed |
| CN-111417642-A | Siloxane compound and method for producing same | 信越化学工业株式会社 | 2020-07-14 | — | — | CN | disclosed |
| EP-2508504-B1 | PROCESS FOR PREPARATION OF CYCLOALKANEDICARBOXYLIC ACID MONOESTERS | SUMITOMO CHEMICAL CO (JP) | 2016-04-13 | — | — | EP | disclosed |
| US-8633304-B2 | Oligonucleotide derivative comprising an aromatic compound | GIFU UNIVERSITY (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8541631-B2 | Surface treatment method for solid material | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-09-24 | — | — | US | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| EP-0444888-A1 | Process for the desilylation of a 4-silyloxy-tetrahydro-pyran-2-one | MERCK & CO. INC. (US) | 1991-09-04 | — | — | EP | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0214708-B1 | GRISEOLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | SANKYO COMPANY LIMITED (JP) | 1989-12-13 | — | — | EP | disclosed |
| EP-0318060-A2 | Griseolic acid derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1989-05-31 | — | — | EP | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |
| EP-0214708-A2 | Griseolic acid derivatives, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1987-03-18 | — | — | EP | disclosed |