Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261121 | 0.80 | DDB1 (0.55) | ALDH1A1MAPTCREBBPDDB1CRBN | |
| SCHEMBL9251370 | 0.80 | DDB1 (0.55) | ALDH1A1GAAMAPTDDB1CRBN | |
| SCHEMBL9253505 | 0.80 | DDB1 (0.55) | ALDH1A1POLBMAPTDDB1CRBN | |
| SCHEMBL17276658 | 0.80 | BRD4 (0.41) | CREBBPDDB1CRBNALOX5NOTUM | |
| SCHEMBL9256649 | 0.79 | CRBN (0.51) | GAACREBBPDDB1CRBN | |
| SCHEMBL8522217 | 0.78 | CRBN (0.47) | ALDH1A1POLBGAAMAPTCREBBP | |
| SCHEMBL11036165 | 0.78 | CRBN (0.47) | ALDH1A1POLBGAAMAPTCREBBP | |
| SCHEMBL8439360 | 0.78 | CRBN (0.47) | ALDH1A1POLBGAAMAPTCREBBP | |
| SCHEMBL17276561 | 0.78 | DDB1 (0.55) | CREBBPDDB1CRBNNOTUM | |
| SCHEMBL8440828 | 0.76 | DDB1 (0.58) | ALDH1A1MAPTCREBBPDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179293-A1 | SMALL MOLECULE ACTIVATORS AND INHIBITORS OF LECITHIN: CHOLESTEROL ACYLTRANSFERASE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-11-26 | — | — | WO | claimed |