Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 3/20 | 0.55 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253505 | 0.80 | DDB1 (0.55) | DDB1CRBNALOX5MAPTMEN1 | |
| SCHEMBL17276398 | 0.80 | ALDH1A1 (0.36) | DDB1CRBNALOX5MAPTALDH1A1 | |
| SCHEMBL9261121 | 0.80 | DDB1 (0.55) | DDB1CRBNALOX5MAPTMEN1 | |
| SCHEMBL8439360 | 0.78 | CRBN (0.47) | DDB1CRBNMAPTMEN1KMT2A | |
| SCHEMBL11036165 | 0.78 | CRBN (0.47) | DDB1CRBNMAPTMEN1KMT2A | |
| SCHEMBL8522217 | 0.78 | CRBN (0.47) | DDB1CRBNMAPTMEN1KMT2A | |
| SCHEMBL17276190 | 0.78 | CREBBP (0.43) | DDB1CRBNMEN1KMT2ASLC6A3 | |
| SCHEMBL17276658 | 0.76 | BRD4 (0.41) | DDB1CRBNALOX5MEN1KMT2A | |
| SCHEMBL8440828 | 0.76 | DDB1 (0.58) | DDB1CRBNALOX5MAPTALDH1A1 | |
| SCHEMBL17276561 | 0.75 | DDB1 (0.55) | DDB1CRBNMEN1KMT2ANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002579-A1 | SUBSTITUTED AZETIDINONE AMIDE DERIVATIVES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | ZENECA LIMITED (GB) | 1995-01-26 | — | — | WO | disclosed |