Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 2/20 | 0.56 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.56 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 7/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR2B | P41595 | 4/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276227 | 0.78 | LDHA (0.38) | DDB1CRBNNOTUMLDHALDHB | |
| SCHEMBL9259633 | 0.75 | CREBBP (0.44) | DDB1CRBNALDH1A1 | |
| SCHEMBL17276266 | 0.72 | MTNR1A (0.43) | ALDH1A1KDM4ELMNAMAPTMEN1 | |
| SCHEMBL22623723 | 0.72 | DDB1 (1.00) | DDB1CRBN | |
| SCHEMBL8439622 | 0.71 | DDB1 (0.56) | DDB1CRBNALDH1A1KDM4EMEN1 | |
| SCHEMBL8863558 | 0.70 | NOTUM (0.45) | DDB1CRBNNOTUMALDH1A1KDM4E | |
| SCHEMBL29484715 | 0.70 | NOTUM (0.45) | DDB1CRBNNOTUMALDH1A1KDM4E | |
| SCHEMBL17276250 | 0.70 | DDB1 (0.55) | DDB1CRBNNOTUMHTR2C | |
| SCHEMBL11036165 | 0.70 | CRBN (0.47) | DDB1CRBNALDH1A1KDM4EMAPT | |
| SCHEMBL8439360 | 0.70 | CRBN (0.47) | DDB1CRBNALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015179293-A1 | SMALL MOLECULE ACTIVATORS AND INHIBITORS OF LECITHIN: CHOLESTEROL ACYLTRANSFERASE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-11-26 | — | — | WO | claimed |