Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 8/20 | 0.44 |
| ▸ | BRD4 | O60885 | 7/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR3A | P46098 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17276227 | 0.79 | LDHA (0.38) | CREBBPBRD4EP300ALDH1A1DDB1 | |
| SCHEMBL8439622 | 0.78 | DDB1 (0.56) | CREBBPBRD4HTR1AHTR3AALDH1A1 | |
| SCHEMBL17276266 | 0.76 | MTNR1A (0.43) | CREBBPBRD4ALDH1A1 | |
| SCHEMBL17276404 | 0.75 | DDB1 (0.56) | ALDH1A1DDB1CRBN | |
| SCHEMBL8522217 | 0.73 | CRBN (0.47) | CREBBPBRD4EP300ALDH1A1DDB1 | |
| SCHEMBL11036165 | 0.73 | CRBN (0.47) | CREBBPBRD4EP300ALDH1A1DDB1 | |
| SCHEMBL8439360 | 0.73 | CRBN (0.47) | CREBBPBRD4EP300ALDH1A1DDB1 | |
| SCHEMBL9257239 | 0.70 | CRBN (0.51) | CREBBPBRD4ALDH1A1DDB1CRBN | |
| SCHEMBL9261121 | 0.69 | DDB1 (0.55) | CREBBPBRD4HTR1AHTR3AALDH1A1 | |
| SCHEMBL2419909 | 0.69 | MEN1 (0.46) | HTR1AHTR3AALDH1A1HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002579-A1 | SUBSTITUTED AZETIDINONE AMIDE DERIVATIVES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS | ZENECA LIMITED (GB) | 1995-01-26 | — | — | WO | disclosed |