Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729064 | 0.90 | CNR1 (0.52) | CNR1HSD11B1SMN1; SMN2SMOCKS1B | |
| SCHEMBL1727675 | 0.83 | CKS1B (0.53) | CNR1SCN9AHTR1ADRD2DRD4 | |
| SCHEMBL3270072 | 0.82 | SCN9A (0.44) | CNR1SCN9ACYP11B2HTR1ADRD2 | |
| SCHEMBL1710740 | 0.81 | CHRM4 (0.48) | CNR1SCN9AHTR1ADRD2DRD4 | |
| SCHEMBL16695413 | 0.80 | NOTUM (0.58) | CNR1SCN9AHTR1ADRD2DRD4 | |
| SCHEMBL27629096 | 0.79 | CKS1B (0.53) | CNR1HSD11B1SMN1; SMN2SMOCKS1B | |
| SCHEMBL1729788 | 0.78 | TDO2 (0.53) | HTR1ADRD4HTR2ADRD3CKS1B | |
| SCHEMBL1579559 | 0.77 | HSD11B1 (0.49) | DRD2DRD3HSD11B1SMN1; SMN2SMO | |
| SCHEMBL3289000 | 0.77 | HTR3E (0.58) | HSD11B1L3MBTL1CKS1BSKP1SKP2 | |
| SCHEMBL5219893 | 0.77 | DRD2 (0.56) | HTR1ADRD2DRD4HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |