Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | LAP3 | P28838 | 2/20 | 0.55 |
| ▸ | ANPEP | P15144 | 2/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.55 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.55 |
| ▸ | IL1RN | P18510 | 5/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.52 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bestatin Methyl Ester SCHEMBL12381043 | 0.91 | ANPEP (0.61) | LAP3ANPEPRNPEPDNPEPIL1RN | |
| Bestatin Methyl Ester SCHEMBL15261304 | 0.91 | ANPEP (0.61) | LAP3ANPEPRNPEPDNPEPIL1RN | |
| Bestatin Methyl Ester SCHEMBL9574604 | 0.91 | ANPEP (0.61) | LAP3ANPEPRNPEPDNPEPIL1RN | |
| SCHEMBL24036408 | 0.88 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPIL1RN | |
| SCHEMBL22703104 | 0.88 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPIL1RN | |
| SCHEMBL9011218 | 0.87 | LTA4H (0.57) | BIRC2MME | |
| SCHEMBL9011222 | 0.87 | LTA4H (0.57) | BIRC2MME | |
| Ubenimex SCHEMBL22632072 | 0.87 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME | |
| Ubenimex SCHEMBL25971 | 0.87 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME | |
| Ubenimex SCHEMBL17889224 | 0.87 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2947070-A1 | MULTI-TARGETED UBENIMEX PRODRUG DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | Weifang Bochuang International Academy of Biotechnology and Medicine (CN) | 2015-11-25 | — | — | EP | disclosed |