Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.55 |
| ▸ | ANPEP | P15144 | 2/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.55 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.55 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.54 |
| ▸ | IL1RN | P18510 | 4/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.52 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.52 |
| ▸ | MME | P08473 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24068219 | 0.91 | LAP3 (0.53) | LAP3ANPEPRNPEPDNPEPBIRC2 | |
| Bestatin Methyl Ester SCHEMBL15261304 | 0.91 | ANPEP (0.61) | LAP3ANPEPRNPEPDNPEPBIRC2 | |
| Bestatin Methyl Ester SCHEMBL9574604 | 0.91 | ANPEP (0.61) | LAP3ANPEPRNPEPDNPEPBIRC2 | |
| Bestatin Methyl Ester SCHEMBL12381043 | 0.91 | ANPEP (0.61) | LAP3ANPEPRNPEPDNPEPBIRC2 | |
| SCHEMBL17278281 | 0.88 | METAP2 (0.55) | LAP3ANPEPRNPEPDNPEPBIRC2 | |
| SCHEMBL24036408 | 0.88 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPBIRC2 | |
| Ubenimex SCHEMBL25971 | 0.87 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME | |
| Ubenimex SCHEMBL5807154 | 0.87 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME | |
| Ubenimex SCHEMBL22632072 | 0.87 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME | |
| Ubenimex SCHEMBL9247599 | 0.87 | MME (0.66) | LAP3ANPEPRNPEPDNPEPMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200371101-A1 | COMPOSITIONS AND METHODS RELATING TO DETECTION, INHIBITION, AND IMAGING OF INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) | REGENERON PHARMACEUTICALS, INC. | 2020-11-26 | — | — | US | disclosed |