Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14946473 | 0.84 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL13256444 | 0.80 | RAB9A (0.71) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL8789904 | 0.77 | MAPK1 (0.75) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL12182366 | 0.76 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL13407919 | 0.74 | HRH3 (0.63) | SMN1; SMN2ALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL8789438 | 0.74 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL19002580 | 0.73 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL8789459 | 0.73 | MAPK1 (0.68) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL13869754 | 0.73 | RAB9A (0.76) | SMN1; SMN2ALDH1A1KDM4EMAPK1RAB9A | |
| SCHEMBL10614647 | 0.72 | NQO1 (0.58) | SMN1; SMN2ALDH1A1KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595995-B1 | HERBICIDAL ISOXAZOLO[5,4-B]PYRIDINES | BASF SE (DE) | 2015-11-25 | — | — | EP | disclosed |