Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17278342 | 0.84 | SMN1; SMN2 (0.70) | ALDH1A1SMN1; SMN2KDM4ERAB9AKMT2A | |
| SCHEMBL14946457 | 0.74 | HSD11B1 (0.51) | SMN1; SMN2RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL14946472 | 0.72 | RIPK1 (0.60) | ALDH1A1SMN1; SMN2KDM4ERAB9AKMT2A | |
| SCHEMBL14946490 | 0.72 | RIPK1 (0.60) | ALDH1A1SMN1; SMN2RAB9AKMT2AMEN1 | |
| SCHEMBL21566734 | 0.71 | NQO1 (0.56) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPK1 | |
| SCHEMBL3963799 | 0.71 | RAB9A (0.63) | ALDH1A1SMN1; SMN2KDM4ERAB9AKMT2A | |
| SCHEMBL13407919 | 0.70 | HRH3 (0.63) | ALDH1A1SMN1; SMN2KDM4EKMT2ALMNA | |
| SCHEMBL8789904 | 0.70 | MAPK1 (0.75) | ALDH1A1SMN1; SMN2KDM4ERAB9AKMT2A | |
| SCHEMBL8789438 | 0.70 | SMN1; SMN2 (0.61) | ALDH1A1SMN1; SMN2KDM4ERAB9AKMT2A | |
| SCHEMBL13869754 | 0.69 | RAB9A (0.76) | ALDH1A1SMN1; SMN2KDM4ERAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10334851-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2019-07-02 | — | — | US | disclosed |
| US-20170367340-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2017-12-28 | — | — | US | disclosed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-9609870-B2 | Herbicidal isoxazolo[5,4-b]pyridines | BASF SE (DE) | 2017-04-04 | — | — | US | disclosed |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | disclosed |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2016-02-11 | — | — | US | disclosed |
| US-9131695-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9131695-B2 | Herbicidal isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2015-09-15 | — | — | US | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | BASF SE (DE) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10334851-B2 | Herbicidal isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | ALDH1A1 292/4885SMN1; SMN2 4074/4885KDM4E 972/4885 |
| US-20130123105-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | ALDH1A1 292/4885SMN1; SMN2 4074/4885KDM4E 972/4885 |
| US-20160037777-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | ALDH1A1 292/4885SMN1; SMN2 4074/4885KDM4E 972/4885 |
| US-20170367340-A1 | Herbicidal Isoxazolo[5,4-B]pyridines | CYP4X1, PNPO, PRDX4 | ALDH1A1 292/4885SMN1; SMN2 4074/4885KDM4E 972/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.