Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | CASR | P41180 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727992 | 0.91 | CASR (0.41) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1729806 | 0.89 | CNR1 (0.44) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1729330 | 0.89 | MCHR1 (0.41) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1728979 | 0.86 | HTR1A (0.43) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1729017 | 0.84 | DRD3 (0.42) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1728853 | 0.84 | CNR1 (0.44) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1730286 | 0.82 | CNR1 (0.44) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1727643 | 0.81 | CNR1 (0.47) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1727631 | 0.81 | HTR1A (0.48) | DRD2DRD3HTR1ADRD4HTR2A | |
| SCHEMBL1727872 | 0.80 | CASR (0.42) | DRD2DRD3HTR1ADRD4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |