Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.52 |
| ▸ | DRD3 | P35462 | 5/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 3/20 | 0.48 |
| ▸ | HTR7 | P34969 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727882 | 0.94 | DRD2 (0.55) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL1727889 | 0.77 | HTR2A (0.51) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL239772 | 0.74 | DRD4 (0.58) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL1727691 | 0.73 | CNR1 (0.41) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL1728577 | 0.73 | DRD2 (0.67) | DRD2DRD3HTR1AHTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL237609 | 0.73 | DRD4 (0.57) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL12229473 | 0.72 | DRD3 (0.61) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL1729971 | 0.72 | CYP11B2 (0.42) | DRD2HTR1AHTR2AHTR7 | |
| SCHEMBL1730370 | 0.72 | CNR1 (0.44) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL1727718 | 0.72 | CNR1 (0.47) | DRD2DRD3HTR1AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |