Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.61 |
| ▸ | HPGDS | O60760 | 1/20 | 0.59 |
| ▸ | ATR | Q13535 | 1/20 | 0.56 |
| ▸ | ALPL | P05186 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280119 | 0.91 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL16179613 | 0.91 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL30932528 | 0.90 | L3MBTL1 (0.68) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL29223523 | 0.90 | L3MBTL1 (0.68) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL11320053 | 0.84 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL2251038 | 0.83 | NPC1 (1.00) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL11312873 | 0.83 | SMN1; SMN2 (0.76) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL11318962 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL2251043 | 0.80 | SMN1; SMN2 (0.87) | SMN1; SMN2NPC1RAB9ANR1H2NR1H3 | |
| SCHEMBL16125579 | 0.78 | SMN1; SMN2 (0.82) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180203175-A1 | TRIAZOLE COMPOUND | Konica Minolta, Inc. (JP) | 2018-07-19 | — | — | US | disclosed |
| US-20180203175-A1 | TRIAZOLE COMPOUND | Konica Minolta, Inc. (JP) | 2018-07-19 | — | — | US | disclosed |
| US-10012777-B2 | Resin composition | Konica Minolta, Inc. (JP) | 2018-07-03 | — | — | US | disclosed |
| US-10012777-B2 | Resin composition | Konica Minolta, Inc. (JP) | 2018-07-03 | — | — | US | disclosed |
| US-20150338563-A1 | RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE | KONICA MINOLTA, INC (JP) | 2015-11-26 | — | — | US | disclosed |
| US-20150338563-A1 | RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE | KONICA MINOLTA, INC (JP) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150338563-A1 | RESIN COMPOSITION, TRIAZOLE COMPOUND, OPTICAL FILM, POLARIZING PLATE, OPTICAL LENS, CIRCULARLY POLARIZING PLATE AND IMAGE DISPLAY DEVICE | HRH3, HELZ, NBAS | SMN1; SMN2 4639/4885NPC1 2503/4885RAB9A 1803/4885 |
| US-10012777-B2 | Resin composition | NBAS, WDR5, HRH3 | SMN1; SMN2 4379/4885NPC1 2768/4885RAB9A 2127/4885 |
| US-20180203175-A1 | TRIAZOLE COMPOUND | H1-10, TTI2, H1-2 | SMN1; SMN2 4539/4885NPC1 2718/4885RAB9A 1962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.