Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.53 |
| ▸ | CKS1B | P61024 | 9/20 | 0.50 |
| ▸ | SKP1 | P63208 | 9/20 | 0.50 |
| ▸ | SKP2 | Q13309 | 9/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727758 | 0.86 | CHRM4 (0.45) | MAPTCHRM4 | |
| SCHEMBL1727542 | 0.85 | HRH3 (0.52) | HCAR2ALDH1A1SMN1; SMN2PDE10A | |
| SCHEMBL3265727 | 0.83 | HCAR2 (0.45) | HCAR2CKS1BSKP1SKP2NPC1 | |
| SCHEMBL1729026 | 0.83 | CHRM4 (0.59) | CHRM4HTR3A | |
| SCHEMBL3267181 | 0.82 | CKS1B (0.44) | HCAR2CKS1BSKP1SKP2NPC1 | |
| SCHEMBL1728734 | 0.81 | CHRM4 (0.51) | CKS1BSKP1SKP2CHRM4HTR3A | |
| SCHEMBL1727741 | 0.81 | CHRM4 (0.56) | ALDH1A1HPGDCHRM4 | |
| SCHEMBL1729046 | 0.79 | CHRM4 (0.45) | MAPTCHRM4 | |
| SCHEMBL1728843 | 0.79 | P2RX7 (0.46) | CHRM4 | |
| SCHEMBL1728737 | 0.78 | HSD11B1 (0.49) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |