Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729687 | 0.86 | LMNA (0.53) | DPP4DPP7HRH3MAPTKDM4E | |
| SCHEMBL1728039 | 0.84 | RXRA (0.42) | DPP4DPP7OPRD1 | |
| SCHEMBL1729368 | 0.83 | NOTUM (0.49) | ADRB1MAPTALDH1A1 | |
| SCHEMBL1729204 | 0.80 | KDM4E (0.44) | DPP4DPP7MAPTKDM4EALDH1A1 | |
| SCHEMBL1730251 | 0.79 | DPP4 (0.42) | DPP4DPP7 | |
| SCHEMBL1730161 | 0.77 | DEGS1 (0.43) | MAPTKDM4EKCNH2 | |
| SCHEMBL1730188 | 0.77 | AKR1C3 (0.39) | DPP4DPP7HRH3CHRM4ACACB | |
| SCHEMBL1729774 | 0.76 | LMNA (0.36) | DPP4DPP7MAPTKDM4EALDH1A1 | |
| SCHEMBL1730303 | 0.76 | LMNA (0.36) | DPP4DPP7 | |
| SCHEMBL1729295 | 0.76 | P4HTM (0.37) | MAPTKDM4EALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |