Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.38 |
| ▸ | ITGAL | P20701 | 6/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 5/20 | 0.35 |
| ▸ | SKP1 | P63208 | 5/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727744 | 0.86 | RXRA (0.43) | RXRAOPRD1ITGB2ICAM1ITGAL | |
| SCHEMBL1728013 | 0.84 | FFAR4 (0.50) | OPRD1DPP4DPP7 | |
| SCHEMBL1727570 | 0.83 | CNR1 (0.39) | COMTCKS1BSKP1SKP2PKM | |
| SCHEMBL1730251 | 0.83 | DPP4 (0.42) | DPP4DPP8DPP9DPP7CKS1B | |
| SCHEMBL1727654 | 0.82 | NPC1 (0.42) | — | |
| SCHEMBL1729204 | 0.81 | KDM4E (0.44) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL1729228 | 0.81 | KMT2A (0.36) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL1729040 | 0.80 | HCAR2 (0.46) | DPP4DPP8DPP9DPP7CKS1B | |
| SCHEMBL1729389 | 0.79 | DPP4 (0.43) | DPP4DPP7 | |
| SCHEMBL1729122 | 0.79 | AKT1 (0.44) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |