Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280297 | 1.00 | CYP2D6 (0.36) | CYP2D6CTSKCTSSTSHRLMNA | |
| SCHEMBL8016917 | 0.83 | CYP2D6 (0.38) | CYP2D6CTSKCTSSCA1CA2 | |
| SCHEMBL3431573 | 0.82 | PDE4A (0.37) | CYP2D6CTSKLMNAKMT2ACA1 | |
| SCHEMBL8017153 | 0.81 | LMNA (0.33) | CYP2D6CTSKCTSSTSHRLMNA | |
| SCHEMBL32663517 | 0.80 | HTT (0.35) | CYP2D6CTSKLMNAKMT2ACA1 | |
| SCHEMBL8030378 | 0.80 | HTT (0.40) | CYP2D6CTSKLMNAKMT2ACA1 | |
| SCHEMBL1845280 | 0.80 | HTT (0.40) | CYP2D6CTSKLMNAKMT2ACA1 | |
| SCHEMBL8028869 | 0.80 | HTT (0.40) | CYP2D6CTSKLMNAKMT2ACA1 | |
| SCHEMBL19407016 | 0.80 | HTT (0.40) | CYP2D6CTSKLMNAKMT2ACA1 | |
| SCHEMBL473223 | 0.79 | TSHR (0.36) | CTSKCTSSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676818-B2 | Toll-like receptor 2-agonistic lipopeptides, and method of making the same | UNIVERSITY OF KANSAS (US) | 2017-06-13 | — | — | US | disclosed |
| US-20150337009-A1 | TOLL-LIKE RECEPTOR 2-AGONISTIC LIPOPEPTIDES, AND METHOD OF MAKING THE SAME | UNIVERSITY OF KANSAS | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150337009-A1 | TOLL-LIKE RECEPTOR 2-AGONISTIC LIPOPEPTIDES, AND METHOD OF MAKING THE SAME | TLR2, TLR3, TLR1 | CYP2D6 4363/4885CTSK 3701/4885CTSS 3622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.