Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.38 |
| ▸ | ITGAL | P20701 | 7/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CKS1B | P61024 | 9/20 | 0.37 |
| ▸ | SKP1 | P63208 | 9/20 | 0.37 |
| ▸ | SKP2 | Q13309 | 9/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727921 | 0.88 | KDM4E (0.43) | THRBCYP2C9 | |
| SCHEMBL1728039 | 0.86 | RXRA (0.42) | RXRAITGB2ICAM1ITGALOPRD1 | |
| SCHEMBL1729264 | 0.84 | HTR3A (0.41) | CKS1BSKP1SKP2 | |
| SCHEMBL1730195 | 0.81 | HCAR2 (0.46) | CKS1BSKP1SKP2 | |
| SCHEMBL1727724 | 0.80 | HSD11B1 (0.40) | CKS1BSKP1SKP2 | |
| SCHEMBL1730156 | 0.80 | DRD2 (0.41) | — | |
| SCHEMBL1727929 | 0.80 | HRH4 (0.42) | — | |
| SCHEMBL1728165 | 0.80 | KDM4E (0.45) | PDE2A | |
| SCHEMBL1728682 | 0.79 | ACACB (0.40) | CKS1BSKP1SKP2 | |
| SCHEMBL1727558 | 0.79 | KCNH2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |