Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1727957 | 0.88 | KDM4E (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1729271 | 0.85 | AKR1C3 (0.43) | DPP4DPP8DPP9DPP7HTR3A | |
| SCHEMBL1730195 | 0.85 | HCAR2 (0.46) | HCAR2NPC1RAB9AMAPTNFKB1 | |
| SCHEMBL1730251 | 0.85 | DPP4 (0.42) | DPP4DPP8DPP9DPP7HTR3A | |
| SCHEMBL1729611 | 0.83 | HTR1A (0.39) | MAPTHTTHTR3ALMNA | |
| SCHEMBL1727570 | 0.81 | CNR1 (0.39) | CKS1BSKP1SKP2 | |
| SCHEMBL1727545 | 0.81 | GRIN2D (0.36) | NFKB1DPP4DPP8DPP9DPP7 | |
| SCHEMBL1730161 | 0.81 | DEGS1 (0.43) | MAPTPDE10AKDM4E | |
| SCHEMBL1730188 | 0.81 | AKR1C3 (0.39) | DPP4DPP8DPP9DPP7PDE10A | |
| SCHEMBL1728022 | 0.81 | FFAR4 (0.34) | DPP4DPP8DPP9DPP7CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |