Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280436 | 0.91 | MEN1 (0.32) | ELANEMEN1KMT2A | |
| SCHEMBL17280447 | 0.90 | ALDH1A1 (0.36) | ALDH1A1GAAELANETNFRSF1ALPAR1 | |
| SCHEMBL17280434 | 0.88 | APEX1 (0.33) | — | |
| SCHEMBL17277942 | 0.86 | APEX1 (0.34) | ALDH1A1GAAELANENR1I2RARA | |
| SCHEMBL17277995 | 0.85 | L3MBTL1 (0.36) | GAAELANE | |
| SCHEMBL17280435 | 0.85 | ELANE (0.30) | ELANE | |
| SCHEMBL17280454 | 0.84 | MEN1 (0.31) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17277958 | 0.82 | MEN1 (0.31) | ELANEMEN1KMT2A | |
| SCHEMBL17280442 | 0.82 | ELANE (0.34) | ELANETNFRSF1AMEN1KMT2A | |
| SCHEMBL17280439 | 0.82 | ELANE (0.31) | ALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221850-B2 | Monophosphite ligands having a tert-butyloxycarbonyl group | EVONIK INDUSTRIES AG (DE) | 2015-12-29 | — | — | US | disclosed |
| US-20150336988-A1 | NOVEL MONOPHOSPHITE LIGANDS HAVING A TERT-BUTYLOXYCARBONYL GROUP | EVONIK INDUSTRIES AG (DE) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336988-A1 | NOVEL MONOPHOSPHITE LIGANDS HAVING A TERT-BUTYLOXYCARBONYL GROUP | TERF2, NUDT1, TERF2IP | ALDH1A1 2538/4885GAA 4543/4885ELANE 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.