Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22747610 | 0.89 | MBOAT4 (0.58) | ALDH1A1ALOX15CTRB1ATMMBOAT4 | |
| SCHEMBL930561 | 0.89 | MBOAT4 (0.58) | ALDH1A1ALOX15CTRB1ATMMBOAT4 | |
| SCHEMBL930559 | 0.89 | MBOAT4 (0.58) | ALDH1A1ALOX15CTRB1ATMMBOAT4 | |
| SCHEMBL14769904 | 0.88 | CTRB1 (0.54) | CTRB1ATMMBOAT4CTSKLMNA | |
| SCHEMBL22118319 | 0.88 | CTRB1 (0.54) | CTRB1ATMMBOAT4CTSKLMNA | |
| SCHEMBL7372388 | 0.88 | CTRB1 (0.54) | CTRB1ATMMBOAT4CTSKLMNA | |
| SCHEMBL8173806 | 0.88 | CTRB1 (0.54) | CTRB1ATMMBOAT4CTSKLMNA | |
| SCHEMBL8232784 | 0.86 | MBOAT4 (0.51) | CTRB1ATMCTSLCTSBMBOAT4 | |
| SCHEMBL29014283 | 0.84 | SYK (0.57) | CTRB1ATMCTSLCTSBMBOAT4 | |
| SCHEMBL25875351 | 0.84 | SYK (0.57) | CTRB1ATMCTSLCTSBMBOAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150336915-A1 | STRUCTURES OF PROTEASOME INHIBITORS AND METHODS FOR SYNTHESIZING AND USE THEREOF | PONO CORPORATION | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336915-A1 | STRUCTURES OF PROTEASOME INHIBITORS AND METHODS FOR SYNTHESIZING AND USE THEREOF | PSMB1, PSMB11, PSMB2 | ALDH1A1 4037/4885ALOX15 3624/4885CTRB1 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.