Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17280953 | 0.90 | CYP1A2 (0.44) | KDM4ECYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL17280946 | 0.83 | CYP1A2 (0.44) | KDM4ECYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL17280952 | 0.81 | GPR3 (0.42) | KDM4ECYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL17280954 | 0.80 | CYP1A2 (0.44) | KDM4ECYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL17280948 | 0.77 | CYP1A2 (0.44) | KDM4ECYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL17280950 | 0.76 | CYP1A2 (0.40) | KDM4ECYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL17280947 | 0.71 | CYP1A2 (0.45) | KDM4ECYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL9768532 | 0.70 | CYP1A2 (0.70) | KDM4ECYP1A2CYP2C19FABP4FABP5 | |
| SCHEMBL13956892 | 0.69 | FABP4 (0.50) | KDM4ECYP1A2CYP2C19ALDH1A1LMNA | |
| SCHEMBL13956894 | 0.68 | FABP4 (0.51) | FABP4FABP5MAOAMAOBACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | ESR1, EPX, SDHB | KDM4E 3138/4885CYP1A2 282/4885CYP2C19 67/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.