Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL781373 | 0.96 | CDK4 (0.39) | PGRAHRCDK4CCND1GABRA1 | |
| SCHEMBL14880906 | 0.95 | PGR (0.38) | PGRAHRKDM4EMAPTKIF11 | |
| SCHEMBL22106242 | 0.93 | PDK2 (0.41) | PGRAHRKDM4EMAPTKIF11 | |
| SCHEMBL802821 | 0.91 | PGR (0.40) | PGRAHRKDM4EMAPTKIF11 | |
| SCHEMBL14979109 | 0.90 | CDK4 (0.39) | PGRAHRCDK4CCND1GABRA1 | |
| SCHEMBL31680 | 0.88 | AHR (0.52) | PGRAHRKDM4EMAPTKIF11 | |
| SCHEMBL29506376 | 0.88 | AHR (0.52) | PGRAHRKDM4EMAPTKIF11 | |
| SCHEMBL13432985 | 0.87 | AHR (0.43) | PGRAHRKDM4EMAPTKIF11 | |
| SCHEMBL16442721 | 0.87 | AHR (0.43) | PGRAHRKDM4EMAPTKIF11 | |
| SCHEMBL21376967 | 0.87 | KIF11 (0.45) | PGRKDM4EMAPTKIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150340627-A1 | MATERIALS FOR ELECTRONIC DEVICES | ESR1, EPX, SDHB | PGR 611/4885AHR 2849/4885KDM4E 3138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.