Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 6/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.70 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP12 | P39900 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17284917 | 0.93 | PRKCA (0.67) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL17281059 | 0.93 | PRKCA (0.67) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL28035112 | 0.88 | PRKCA (0.75) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL28901133 | 0.83 | PRKCA (0.72) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Calceolarioside B SCHEMBL30913582 | 0.82 | PRKCA (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Calceolarioside B SCHEMBL29785210 | 0.82 | PRKCA (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Calceolarioside B SCHEMBL17173771 | 0.82 | PRKCA (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| Calceolarioside B SCHEMBL27983548 | 0.82 | PRKCA (1.00) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL17173773 | 0.81 | PRKCA (0.86) | PRKCACYP19A1MMP2MMP3MMP9 | |
| SCHEMBL17177798 | 0.79 | PRKCA (0.79) | PRKCACYP19A1MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150337001-A1 | ASTER GLEHNI EXTRACTS, FRACTIONS OR COMPOUNDS ISOLATED THEREFROM FOR THE TREATMENT OR PREVENTION OF HYPERURICEMIA OR GOUT | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150337001-A1 | ASTER GLEHNI EXTRACTS, FRACTIONS OR COMPOUNDS ISOLATED THEREFROM FOR THE TREATMENT OR PREVENTION OF HYPERURICEMIA OR GOUT | HADH, GGH, ARF6 | PRKCA 1760/4885CYP19A1 3086/4885MMP2 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.