SCHEMBL8944304

SCHEMBL8944304

CC(COc1ccc(N(c2ccccc2)c2ccccc2)cc1)Oc1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.44
HPGD P15428 2/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
XBP1 P17861 1/20 0.42
MAOA P21397 1/20 0.41
PTGS1 P23219 1/20 0.41
NPC1 O15118 1/20 0.40
MTOR P42345 1/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
MAPK1 P28482 1/20 0.40
CYP2C19 P33261 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CHRNB2 P17787 1/20 0.39
CHRNA7 P36544 1/20 0.39
KDM4E B2RXH2 1/20 0.39
GMNN O75496 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8944273 0.94 KMT2A (0.42) LMNAHPGDPOLBMAPTXBP1
SCHEMBL17281130 0.84 MAPT (0.53) LMNAHPGDPOLBMAPTXBP1
SCHEMBL2505117 0.84 LMNA (0.61) LMNAMAOAPTGS1CYP2D6
SCHEMBL9768704 0.83 LTA4H (0.58) LMNAHPGDPOLBMAPTXBP1
SCHEMBL8943823 0.81 ACHE (0.44) LMNAHPGDPOLBMAPTMAOA
SCHEMBL8670952 0.79 LMNA (0.52) LMNAHPGDPOLBMAPTXBP1
SCHEMBL8436949 0.79 LMNA (0.52) LMNAMAPTMAOAPTGS1TP53
SCHEMBL8436935 0.79 LMNA (0.52) LMNAMAPTMAOAPTGS1TP53
SCHEMBL14011821 0.79 MAPT (0.43) LMNAPOLBMAPTHSD17B10SMN1; SMN2
SCHEMBL9768614 0.78 NQO1 (0.58) LMNAHPGDMAPTKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5480765-A PRESSURE AND HEAT SENSITIVE PAPER, IMPROVED PHOTOSTABILITY BY ADDITION OF TRIARYLAMINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1996-01-02 US disclosed