Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL174438 | 0.88 | GSK3A (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19GSK3A | |
| SCHEMBL16004447 | 0.67 | MAPT (0.39) | ALDH1A1GSK3AGSK3BMEN1MAPK1 | |
| SCHEMBL16322600 | 0.61 | ALDH1A1 (0.56) | ALDH1A1CYP2C9CYP2C19GSK3AGSK3B | |
| SCHEMBL14645219 | 0.61 | ALDH1A1 (0.56) | ALDH1A1CYP2C9CYP2C19GSK3AGSK3B | |
| SCHEMBL11610267 | 0.56 | ALDH1A1 (0.36) | ALDH1A1CYP3A4GSK3AGSK3BMAPK1 | |
| SCHEMBL11847806 | 0.56 | GSK3A (0.54) | ALDH1A1CYP3A4CYP2C9CYP2C19GSK3A | |
| SCHEMBL3380745 | 0.54 | — | — | |
| SCHEMBL12310819 | 0.54 | MAPK1 (0.46) | ALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL13301040 | 0.52 | ACHE (0.47) | ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL3414903 | 0.50 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9CYP2C19GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2386203-B1 | Use of dithiin tetracarboximides for combating phytopathogenic fungi | BAYER CROPSCIENCE AG (DE) | 2013-11-20 | — | — | EP | claimed |
| US-9095140-B2 | Use of dithiine-tetracarboximides for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| US-20150065551-A1 | Use of Dithiine-tetracarboximides for Controlling Phytopathogenic Fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-03-05 | — | — | US | disclosed |
| US-8865759-B2 | Use of dithiine-tetracarboximides for controlling phytopathogenic fungi | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-21 | — | — | US | disclosed |
| EP-2386203-B1 | Use of dithiin tetracarboximides for combating phytopathogenic fungi | BAYER CROPSCIENCE AG (DE) | 2013-11-20 | — | — | EP | disclosed |
| US-20110319462-A1 | Use of Dithiine-tetracarboximides for Controlling Phytopathogenic Fungi | BAYER CROPSCIENCE AG | 2011-12-29 | — | — | US | disclosed |
| EP-2271219-B1 | USE OF DITHIIN TETRACARBOXIMIDES FOR TREATING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-20100120884-A1 | USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI | BAYER CROPSCIENCE AG (DE) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120884-A1 | USE OF DITHIINE-TETRACARBOXIMIDES FOR CONTROLLING PHYTOPATHOGENIC FUNGI | TST, TTI1, DPM1 | ALDH1A1 4094/4885CYP1A2 4140/4885CYP3A4 3851/4885 |
| US-20110319462-A1 | Use of Dithiine-tetracarboximides for Controlling Phytopathogenic Fungi | TST, TTI1, DPM1 | ALDH1A1 4094/4885CYP1A2 4140/4885CYP3A4 3851/4885 |
| US-20150065551-A1 | Use of Dithiine-tetracarboximides for Controlling Phytopathogenic Fungi | TST, TTI1, DPM1 | ALDH1A1 4094/4885CYP1A2 4140/4885CYP3A4 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.