Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PANK3 | Q9H999 | 7/20 | 0.45 |
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | LCAT | P04180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2306277 | 1.00 | GPR119 (0.47) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| SCHEMBL12153075 | 1.00 | GPR119 (0.47) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| SCHEMBL1728173 | 1.00 | GPR119 (0.47) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| SCHEMBL29940306 | 0.84 | KDM4E (0.50) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| SCHEMBL22754620 | 0.79 | JAK1 (0.46) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| Hydrochloric Acid SCHEMBL21522335 | 0.79 | KDM4E (0.45) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| SCHEMBL21853958 | 0.79 | PANK3 (0.47) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| SCHEMBL12099334 | 0.79 | GPR119 (0.55) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| SCHEMBL16718810 | 0.78 | KDM4E (0.50) | GPR119KDM4EALDH1A1L3MBTL1PANK3 | |
| SCHEMBL16478649 | 0.78 | KDM4E (0.54) | GPR119KDM4EALDH1A1L3MBTL1PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932844-B1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | NIPPON SODA CO (JP) | 2015-09-02 | — | — | EP | disclosed |
| US-8697867-B2 | Cross-linked cyclic amine compounds and agents for pest control | NIPPON SODA CO., LTD. (JP) | 2014-04-15 | — | — | US | disclosed |
| US-20130331569-A1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | NIPPON SODA CO., LTD. (JP) | 2013-12-12 | — | — | US | disclosed |
| US-8536340-B2 | Cross-linked cyclic amine compounds and agents for pest control | NIPPON SODA CO., LTD. (JP) | 2013-09-17 | — | — | US | disclosed |
| US-8338607-B2 | Cyclic amine compounds and agents for pest control | NIPPON SODA CO., LTD. (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-1947098-B1 | CYCLIC AMINE COMPOUNDS AND PEST CONTROL AGENT | NIPPON SODA CO (JP) | 2011-11-30 | — | — | EP | disclosed |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | NIPPON SODA CO., LTD. (JP) | 2009-12-24 | — | — | US | disclosed |
| US-20090259046-A1 | Cyclic Amine Compounds and Agents for Pest Control | NIPPON SODA CO., LTD. (JP) | 2009-10-15 | — | — | US | disclosed |
| EP-1947098-A1 | CYCLIC AMINE COMPOUNDS AND PEST CONTROL AGENT | NIPPON SODA CO., LTD. (JP) | 2008-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090259046-A1 | Cyclic Amine Compounds and Agents for Pest Control | NPR1, CYCS, CYC1 | GPR119 3842/4885KDM4E 1178/4885ALDH1A1 2594/4885 |
| US-20130331569-A1 | CROSS-LINKED CYCLIC AMINE COMPOUNDS AND AGENTS FOR PEST CONTROL | CYCS, NPY1R, CYBB | GPR119 2283/4885KDM4E 1600/4885ALDH1A1 3259/4885 |
| US-20090318694-A1 | Cross-Linked Amine Compounds and Agents for Pest Control | CYCS, NPY1R, CYBB | GPR119 2518/4885KDM4E 1474/4885ALDH1A1 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.