Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138 | 0.75 | MAPT (0.32) | NPSR1MAPTTSPOKDM4ETP53 | |
| SCHEMBL895206 | 0.72 | ALDH1A1 (0.47) | ALDH1A1CYP3A4MEN1KMT2AL3MBTL1 | |
| SCHEMBL8613 | 0.72 | TP53 (0.43) | ALDH1A1CYP3A4NPSR1CYP1A2CYP2D6 | |
| SCHEMBL845050 | 0.71 | MAPT (0.37) | ALDH1A1CYP3A4MAPK14MAPTTSHR | |
| SCHEMBL1728325 | 0.71 | ALDH1A1 (0.41) | ALDH1A1CYP3A4NPSR1CYP1A2CYP2D6 | |
| SCHEMBL1883808 | 0.71 | ALDH1A1 (0.41) | ALDH1A1CYP3A4NPSR1CYP1A2CYP2D6 | |
| SCHEMBL714757 | 0.69 | L3MBTL1 (0.36) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL1725922 | 0.68 | MAPT (0.51) | ALDH1A1CYP3A4CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL6976100 | 0.64 | CYP3A4 (0.58) | ALDH1A1CYP3A4NPSR1CYP1A2CYP2D6 | |
| SCHEMBL10965817 | 0.64 | MEN1 (0.42) | ALDH1A1CYP3A4NPSR1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403847-A1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB Pharma, S.A. (BE) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100405-A1 | TRIAZINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-09-10 | — | — | WO | disclosed |